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Double- and single-differential cross sections for inclusive charged-current ${\nu }_{\mu }$-nucleus scattering are reported for the kinematic domain 0 to $2\mathrm{GeV}/c$in three-momentum transfer and 0 to 2 GeV in available energy, at a mean ${\nu }_{\mu }$energy of 1.86 GeV. The measurements are based on an estimated 995,760 ${\nu }_{\mu }$charged-current (CC) interactions in the scintillator medium of the NOvA Near Detector. The subdomain populated by 2-particle-2-hole (2p2h) reactions is identified by the cross section excess relative to predictions for ${\nu }_{\mu }$-nucleus scattering that are constrained by a data control sample. Models for 2-particle-2-hole processes are rated by ${\chi }^2$comparisons of the predicted-versus-measured ${\nu }_{\mu }$CC inclusive cross section over the full phase space and in the restricted subdomain. Shortfalls are observed in neutrino generator predictions obtained using the theory-based València and SuSAv2 2p2h models. Published by the American Physical Society2025 

We report a search for neutrino oscillations to sterile neutrinos under a model with three active and one sterile neutrinos ( $3+1$model). This analysis uses the NOvA detectors exposed to the NuMI beam, running in neutrino mode. The data exposure, $13.6\times {10}^{20}$protons on target, doubles that previously analyzed by NOvA, and the analysis is the first to use ${\nu }_{\mu }$charged-current interactions in conjunction with neutral-current interactions. Neutrino samples in the near and far detectors are fitted simultaneously, enabling the search to be carried out over a $\mathrm{\Delta }{m}_{41}^2$range extending 2 (3) orders of magnitude above (below) $1{\mathrm{eV}}^2$. NOvA finds no evidence for active-to-sterile neutrino oscillations under the $3+1$model at 90% confidence level. New limits are reported in multiple regions of parameter space, excluding some regions currently allowed by IceCube at 90% confidence level. We additionally set the most stringent limits for anomalous ${\nu }_{\tau }$appearance for $\mathrm{\Delta }{m}_{41}^2\le 3{\mathrm{eV}}^2$. Published by the American Physical Society2025 

Abstract Measuring observables to constrain models using maximum-likelihood estimation is fundamental to many physics experiments. Wilks' theorem provides a simple way to construct confidence intervals on model parameters, but it only applies under certain conditions. These conditions, such as nested hypotheses and unbounded parameters, are often violated in neutrino oscillation measurements and other experimental scenarios. Monte Carlo methods can address these issues, albeit at increased computational cost. In the presence of nuisance parameters, however, the best way to implement a Monte Carlo method is ambiguous. This paper documents the method selected by the NOvA experiment, the profile construction. It presents the toy studies that informed the choice of method, details of its implementation, and tests performed to validate it. It also includes some practical considerations which may be of use to others choosing to use the profile construction. 

ABSTRACT SalmonellaOuter Membrane Vesicles (OMVs) were recently shown to inhibit P22 bacteriophage infection. Furthermore, despite there being several published reports now independently describing (1) the marked prevalence of tRFs within secreted vesicle transcriptomes and (2) roles for specific tRFs in facilitating/inhibiting viral replication, there have been no examinations of the effects of vesicle-secreted tRFs on viral infection reported to date. Notably, while specific tRFs have been reported in a number of bacteria, the tRFs expressed by salmonellae have not been previously characterized. As such, we recently screened small RNA-seq datasets for the presence of recurrent, specifically excised tRFs and identified 31 recurrent, relatively abundant tRFs expressed bySalmonella entericaserovar Typhimurium (SL1344). What’s more, we findS. Typhimurium OMVs contain significant levels of tRFs highly complementary to knownSalmonella enterica-infecting bacteriophage with 17 of 31 tRFs bearing marked complementarity to at least one knownSalmonella enterica-infecting phage (averaging 97.4% complementarity over 22.9 nt). Most notably, tRNA-Thr-CGT-1-1, 44-73, bears 100% sequence complementary over its entire 30 nt length to 29 distinct, annotatedSalmonella enterica-infecting bacteriophage including P22. Importantly, we find inhibiting this tRF in secreted OMVs improves P22 infectivity in a dose dependent manner whereas raising OMV tRF levels conversely inhibits P22 infectivity. Furthermore, we find P22 phage pre-incubation with OMVs isolated from naïve, control SL1344S. Typhimurium, successfully rescues the ability ofS. Typhimurium transformed with a specific tRNA-Thr-CGT-1-1, 44-73 tRF inhibitor to defend against P22. Collectively, these experiments confirm tRFs secreted inS. Typhimurium OMVs are directly involved with and required for the ability of OMVs to defend against bacteriophage predation. As we find the majority of OMV tRFs are highly complementary to an array of knownSalmonella enterica-infecting bacteriophage, we suggest OMV tRFs may primarily function as a broadly acting, previously uncharacterized innate antiviral defense. 

This Letter reports a search for charge-parity ( $CP$) symmetry violating nonstandard interactions (NSI) of neutrinos with matter using the NOvA Experiment, and examines their effects on the determination of the standard oscillation parameters. Data from ${\nu }_{\mu }\left({\overline{\nu }}_{\mu }\right)\to {\nu }_{\mu }\left({\overline{\nu }}_{\mu }\right)$and ${\nu }_{\mu }\left({\overline{\nu }}_{\mu }\right)\to {\nu }_e\left({\overline{\nu }}_e\right)$oscillation channels are used to measure the effect of the NSI parameters ${ϵ}_{e\mu }$and ${ϵ}_{e\tau }$. With 90% CL the magnitudes of the NSI couplings are constrained to be $\left|{ϵ}_{e\mu }\right|\lesssim 0.3$and $\left|{ϵ}_{e\tau }\right|\lesssim 0.4$. A degeneracy at $\left|{ϵ}_{e\tau }\right|\approx 1.8$is reported, and we observe that the presence of NSI limits sensitivity to the standard $CP$phase ${\delta }_{CP}$. Published by the American Physical Society2024 

NOvA is a long-baseline neutrino oscillation experiment that measures oscillations in charged-current ${\nu }_{\mu }\to {\nu }_{\mu }$(disappearance) and ${\nu }_{\mu }\to {\nu }_e$(appearance) channels, and their antineutrino counterparts, using neutrinos of energies around 2 GeV over a distance of 810 km. In this work we reanalyze the dataset first examined in our previous paper [] using an alternative statistical approach based on Bayesian Markov chain Monte Carlo. We measure oscillation parameters consistent with the previous results. We also extend our inferences to include the first NOvA measurements of the reactor mixing angle ${\theta }_{13}$, where we find $0.071\le {\sin }^{2}2{\theta }_{13}\le 0.107$, and the Jarlskog invariant, where we observe no significant preference for the $CP$-conserving value $J=0$over values favoring $CP$violation. We use these results to examine the effects of constraints from short-baseline measurements of ${\theta }_{13}$using antineutrinos from nuclear reactors when making NOvA measurements of ${\theta }_{23}$. Our long-baseline measurement of ${\theta }_{13}$is shown to be consistent with the reactor measurements, supporting the general applicability and robustness of the Pontecorvo-Maki-Nakagawa-Sakata framework for neutrino oscillations. Published by the American Physical Society2024 

We measure the branching fraction and $CP$-violating flavor-dependent rate asymmetry of $B^0\to {\pi }^0{\pi }^0$decays reconstructed using the Belle II detector in an electron-positron collision sample containing $387\times {10}^6\mathrm{\Upsilon }\left(4S\right)$mesons. Using an optimized event selection, we find $125\pm 20$signal decays in a fit to background-discriminating and flavor-sensitive distributions. The resulting branching fraction is $(1.25\pm 0.23)\times {10}^{-6}$and the $CP$-violating asymmetry is $0.03\pm 0.30$. Published by the American Physical Society2025